Alpha-halocarboxylic acids and derivatives
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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences Sodium iodoacetate BioUltra, >=98% | 305-53-3 | MFCD00002686 | 5G
Sodium iodoacetate BioUltra, >=98% | Purity: >=98% | Mol Wt: 207.93 | 305-53-3 | MFCD00002686 | 5G
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AdipoGen GE23077 A1 B1
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Chemical. CAS 752989-46-1, 752989-45-0752989-44-9. Formula C31H51N9O16, C31H49N9O16. MW 805.8803.8. Isolated from Actinomadura sp. Cyclic heptapeptide antibiotic. Potent and selective inhibitor of bacterial RNA polymerase RNAP. Inhibits Gram-positive Bacillus subtilis and Gram-negative Escherichia coli RNAPs with IC50 ~20nM, whereas it is not active on E. coli DNA polymerase or on eukaryotic wheat germ RNAP II IC50 values >100µM. Even though of its potent activity in vitro on purified bacterial RNAPs, it shows a narrow spectrum of antimicrobial activity in vivo on Gram-positive and Gram-negative bacteria, due to lack of memmbrane permeability. Acts at the level of transcription initiation. Binds directly to the bacterial RNA polymerase RNAP active-center i and i1 nucleotide binding sites, preventing the binding of initiating nucleotides and thereby preventing transcription initiation.
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Medchemexpress LLC ODN 2216 sodium | 98.6% | 6432 (free acid) | 10 MG
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ODN 2216 sodium is a synthetic oligodeoxynucleotide (sodium salt) that functions as a human-specific TLR9 ligand. It strongly induces type I interferons (IFN-α and IFN-β) via plasmacytoid dendritic cells and promotes IL-12 and IFN-γ production in immune cell assays, making it useful for in vitro and ex vivo immunology research focused on innate immune activation.
- Human-specific TLR9 agonist.
- Induces high levels of IFN-α and IFN-β.
- Stimulates IL-12 production by dendritic cells.
- Activates NK cells and promotes IFN-γ production in CD4+ T cells.
- Supplied as the sodium salt suitable for in vitro use.
- High purity (98.6%) and provided as a 10 MG quantity.
- Oligonucleotide sequence provided to support experimental design.
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TARGETMOL CHEMICALS INC ADH-503 25MG
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. purity: 98%
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Cayman Chemical icFSP1 trifluoroacetate salt
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An inhibitor of FSP1; induces condensation and phase separation of FSP1 in cells at 2.5 µM; does not inhibit FSP1 enzymatic activity in a cell-free assay (IC50 = > 30 µM); induces ferroptosis in HT-1080 fibrosarcoma cells; decreases tumor volume and weight in a B16/F10 murine melanoma model using human FSP1-overexpressing, Gpx4-/-Fsp1-/- B16/F10 cells at 50 mg/kg
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Medchemexpress LLC Trigonelline | 535-83-1 | MFCD00054262 | 100.0% | 137.14 g/mol | C7H7NO2 | 10 MG
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Trigonelline is a naturally occurring alkaloid used as a research reagent and analytical standard. It functions as an Nrf2 inhibitor and has reported antidiabetic, antibacterial, antifungal, and antiviral activities, and can induce ferroptosis. Supplied as a white to light yellow solid, it is intended for biological assays and analytical applications.
- High purity suitable for analytical and biological studies.
- Well-characterized molecular weight and chemical formula.
- Available in small milligram quantities for research use.
- Solid form; store protected from light at recommended temperatures.
- Appropriate as a reference standard for Nrf2 and apoptosis research.
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Sigma Aldrich Fine Chemicals Biosciences Iodoacetic acid | 64-69-7 | MFCD00002685 | 10g
Iodoacetic acid | Purity: 98% | Mol Wt: 185.95 | 64-69-7 | MFCD00002685 | 10g
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Medchemexpress LLC Hyaluronic Acid Sod 10Mg | HY-B0633D-10MG
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Hyaluronic Acid Sod 10Mg
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000343187 RP-8-PCPT-CGMPS SOD 1MG
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Cayman Chemical Gap 27 trifluoroacetate salt
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A connexin-mimetic peptide; reduces survival of isolated rat osteoclasts at 500 µM; decreases bone resorption in rat bone slice and osteoclast co-cultures; accelerates wound closure and stratification of the corneal epithelium in isolated human corneas; reduces cardiac remodeling and the incidence of cardiac arrhythmias in a rat model of AV-shunt surgery-induced high-output heart failure
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eMolecules 3-Methoxypropionic acid hydrazide | 21920-89-8 | MFCD03789158 | 5g
Oakwood Chemicals | 3-Methoxypropionic acid hydrazide | 5g | 480115949 | 019318 | | 21920-89-8 | MFCD03789158 | 118.136 | C4H10N2O2
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000414289 SODIUM IODOACETATE 25G
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eMolecules EMOLECULES INC
5000492868 BENZYL 2-BROMOACETATE 100G
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Sigma Aldrich Fine Chemicals Biosciences tert-Butyl chloroacetate 97% | 107-59-5 | MFCD00000930 | 25G
tert-Butyl chloroacetate 97% | Purity: 97% | Mol Wt: 150.6 | 107-59-5 | MFCD00000930 | 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000449981 3-BROMOPHENYLACETIC 25G
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